IND for COVID-19 with Opaganib Submitted to the FDA by RedHill Biopharma

Proposed study intended to evaluate the safety and efficacy of opaganib in up to 60 patients hospitalized with positive SARS-CoV-2 infection and pneumonia in the U. RedHill preparing for potential ramp-up of manufacturing of opaganib. The proposed randomized, double-blind, placebo-controlled Phase 2a study is intended to evaluate the safety and efficacy of opaganib in up to 60 adult patients hospitalized with positive SARS-CoV-2 and pneumonia in the U. Levitt, MD, Ph. A compassionate use program with opaganib is ongoing in Israel, with five patients treated to date in a leading hospital. Preliminary findings from all five patients have shown an improved C-Reactive Protein CRP , an inflammatory biomarker, with four of the five patients also demonstrating measurable clinical improvement, including reduced supplemental oxygenation and higher lymphocyte counts within days following treatment initiation with opaganib. In order to facilitate access to opaganib, various programs are currently under discussion in other countries.

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RedHill Biopharma Receives Approval for COVID-19 Phase 2/3 Study with Opaganib in the UK

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Bus services may be altered or reduced due to the coronavirus situation. Whilst known information will be published on the buses temporary changes page and highlighted by message on the individual timetable pages , it is suggested that you contact the operator or visit their website or social media , before travelling. Please note: If a service is marked as ‘due to change’ please check the forthcoming bus timetable changes page for the most up-to-date information.

Services are operated with low-floor fully-accessible buses, unless stated. For services marked “wheelchair-accessible vehicle”, wheelchairs may be loaded by means of a lift.

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